发明名称 INHIBITORS OF SRC AND OTHER PROTEIN KINASES
摘要 The present invention provides compounds of formula I:wherein A is N or CR, and G, R1, R2, and R3 are as described in the specification. These compounds are inhibitors of protein kinase, particularly inhibitors of Src mammalian protein kinase involved in cell proliferation, cell death and response to extracellular stimuli. The invention also relates to methods for producing these inhibitors. The invention also provides pharmaceutical compositions comprising the inhibitors of the invention and methods of utilizing those compositions in the treatment and prevention of various disorders.
申请公布号 WO02092573(A2) 申请公布日期 2002.11.21
申请号 WO2002US15606 申请日期 2002.05.16
申请人 VERTEX PHARMACEUTICALS INCORPORATED;MOON, YOUNG-CHOON 发明人 MOON, YOUNG-CHOON
分类号 C07D401/04;A61F2/00;A61F9/00;A61K9/00;A61K31/4439;A61K31/496;A61K31/506;A61K31/5377;A61K45/00;A61P1/04;A61P1/18;A61P3/10;A61P11/06;A61P13/12;A61P19/08;A61P19/10;A61P25/00;A61P25/02;A61P25/14;A61P25/16;A61P25/28;A61P29/00;A61P31/04;A61P35/00;A61P37/02;A61P37/06;A61P37/08;A61P43/00;C07D401/14;C07D403/04;C07D403/14;C07D405/14;C07D409/14;C07D417/14 主分类号 C07D401/04
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