发明名称 Sulphonyloxazolamines as therapeutic active ingredients
摘要 The present invention relates to sulphonylexazolamines of general formula (I), wherein R1, R2 represent independently from each other H, A, -(CH2)n-Ar or alkenyl with 2-6 C atoms, R1 and R2 together also represent a mononuclear saturated heterocycle with 1-2 N, O and/or S atoms, Z is H, A, CF3, NO2, Hal, OH, OA, NH2, NHA or NH2. A represents alkyl with 1-6 C atoms, Ar is Z-monosubstituted or Z-disubstituted phenyl, Hal is F, Cl, Br, or L n is 1 or 2 of the physiologically acceptable salts or solvates thereof. Said sulphonyloxazolamines are used as therapeutic active ingredients. The invention also relates to the use of sulphonyloxazolamines as therapeutic active ingredients and/or to the production of pharmaceutical preparations to combat diseases of the central nervous system. The invention further relates to a pharmaceutical preparation and the production thereof.
申请公布号 US6441013(B1) 申请公布日期 2002.08.27
申请号 US20010868097 申请日期 2001.06.14
申请人 MERCK PATENT GMBH 发明人 GREINER HARTMUT;BARTOSZYK GERD;BOETTCHER HENNING;BARNICKEL GERHARD;CEZANNE BERTRAM
分类号 A61K31/421;A61K31/454;A61K31/5377;A61P25/00;A61P25/16;A61P25/18;A61P25/24;A61P25/28;C07D263/48;(IPC1-7):A61K31/42 主分类号 A61K31/421
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