DERIVATI MULTIFUNZIONALI DEL POLIETILENGLICOLE LORO PREPARAZIONE ED IMPIEGO

摘要

The present invention refers to complex-structured multifunctional polyethylene glycol derivatives (multiPEG) obtained by assembling single PEG units with a defined molecular weight through a polyfunctional linker. The assembling of single ,PEG units gives polyfunctional multimeric systems characterized by a high molecular weight, low polydispersity and a binding capacity higher than that of a commercial PEG of equal size. Said multiPEG systems may be used as carriers and stabilisers of pharmacologically or biologically active substances as well as of reagents and catalysts for liquid-phase synthesis reactions and as soluble support in synthetic processes.