| 摘要 |
PROBLEM TO BE SOLVED: To obtain an intraoral dissolution type tablet that includes liposoluble medicines such as vitamin E group, vitamin K group, and the like, and shows excellent intraoral disintegration. SOLUTION: The objective intraoral dissolution type tablet is obtained by tabletting the moistened powder that includes a water-soluble polymeric substance, liposoluble medicines that are uniformly dispersed in the polymeric substance and excipient as saccharides by means of a wet type tabletting machine. The liposoluble medicines are readily dispersed in the water-soluble polymeric substance uniformly by spray-drying an emulsion including the needed components, and the objective process for producing the moistened tablets can also be provided by using the spray-dried product.
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