发明名称 |
Method of using (+) cisapride for the treatment of gastro-esophageal reflux disease and other disorders |
摘要 |
<p>A composition comprising (+) cisapride, or a pharmaceutically acceptable salt thereof, wherein: The composition is for eliciting an antiemetic effect in a human by administering an amount thereof sufficient to alleviate nausea and vomiting whilst being insufficient to cause adverse side-effects associated with the administration of racemic cisapride, or while achieving a higher bioavailability than achieved with racemic cisapride; or the composition is for treating a condition caused by gastrointestinal motility dysfunction in a human by administering an amount thereof sufficient to alleviate said condition whilst being insufficient to cause adverse side-effects associated with the administration of racemic cisapride, or while achieving a higher bioavailability than achieved with racemic cisapride, and wherein the (+)-cisapride or pharmaceutically acceptable salt thereof comprises at least 90% by weight of the total amount of cisapride in the composition.</p> |
申请公布号 |
EP1170010(A2) |
申请公布日期 |
2002.01.09 |
申请号 |
EP20010113440 |
申请日期 |
1993.07.06 |
申请人 |
SEPRACOR INC. |
发明人 |
GRAY, NANCY, M.;YOUNG, JAMES W. |
分类号 |
C07D211/62;A61K31/445;A61K31/4468;A61P1/00;A61P1/08;A61P1/10;A61P1/14;(IPC1-7):A61K31/446 |
主分类号 |
C07D211/62 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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