| 发明名称 |
A METHOD OF TREATING CANCER |
| 摘要 |
The present invention relates to methods of treating cancer using a combination of a compound which is an antineoplastic agent and a compound which is a inhibitor of prenyl-protein transferase, which methods comprise administering to said mammal, either sequentially in any order or simultaneously, amounts of at lest two therapeutic agents selected from a group consisting of a compound which is an antineoplastic agent and a compound which is an inhibitor or prenyl-protein transferase. The invention also relates to methods of preparing such compositions.
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| 申请公布号 |
CA2292471(A1) |
申请公布日期 |
1998.12.10 |
| 申请号 |
CA19982292471 |
申请日期 |
1998.06.04 |
| 申请人 |
MERCK & CO., INC.;SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH |
发明人 |
MOASSER, MARK M.;PRENDERGAST, GEORGE C.;GRAHAM, SAMUEL L.;GIBBS, JACKSON B.;ROSEN, NEAL;KOHL, NANCY;SEPP-LORENZINO, LAURA;OLIFF, ALLEN I. |
| 分类号 |
C07D233/64;A61K31/198;A61K31/223;A61K31/4178;A61K31/4439;A61K31/495;A61K31/496;A61K31/497;A61K31/506;A61K35/00;A61K41/00;A61K45/06;A61P43/00;C07C323/25;C07D241/04;C07D307/33;C07D401/04;C07D401/06;C07D401/10;C07D401/14;C07D403/06;C07D403/10;C07D403/12;(IPC1-7):A01N43/50;A61K31/415;A01N43/60 |
主分类号 |
C07D233/64 |
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