发明名称 USE OF ALPHA-21 SELECTIVE ADRENERGIC RECEPTOR AGONISTS IN MEMORY ENHANCEMENT
摘要 Disclosed is a composition for treating memory disorders and cognitive decline, e.g., age-related cognitive decline, in a primate which includes a therapeutically effective amount of an alpha-2 agonist having a high affinity for the alpha-2I subtype, e.g., guanfacine and guanabenz or a nontoxic, pharmaceutically acceptable salt thereof. Particularly preferred is the use of alpha-2I selective agonists such as guanfacine.
申请公布号 CA1307741(C) 申请公布日期 1992.09.22
申请号 CA19870551279 申请日期 1987.11.06
申请人 ARNSTEN, AMY F.T. 发明人 ARNSTEN, AMY F.T.;GOLDMAN-RAKIC, PATRICIA S.
分类号 A61K31/155;A61K31/165;A61P25/28 主分类号 A61K31/155
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