MULTIPLE GLAZING A spacer frame for use in the manufacture of a multiple glazing unit by a process in which the spacer frame is disposed between prepared transparent panels and the panels are pressed together. The spacer frame comprises one or more spacer elements having bent corners or four hollow profiles joined at their ends by corner pieces or welding. The hollow profiles each have two parallel portions intended to be located in juxtaposed relation to and parallel with the transparent panels. A bridging portion extends between the parallel portions and located at the outer region of the spacer frame and arranged to provide a closed figure of at least substantially uniform thickness. A coating of a curing sealant composition is disposed on outer surfaces of the closed figure. The coating of sealant composition extends along the parallel portions of the profiles and over the bridging portions of the profiles. The coating is of sufficient thickness and distribution to form a moisture resistant seal between the spacer elements and the transparent panels.