| 摘要 |
A method of isolating fetal nucleated cells, particularly fetal nucleated erythrocytes, from a maternal blood sample, by means of an antigen present on the cell surface of the fetal erythrocytes. A method of detecting fetal DNA of interest, which is a gene or gene portion associated with a disease or condition, a chromosomal abnormality or sex-specific DNA, in a maternal blood sample. The presence or absence, as well as the quantity of fetal DNA of interest in a maternal sample can be determined. The claimed method of detection can be used prenatally or postnatally and is particularly useful because it is non-invasive and can be carried out early in pregancy. <IMAGE> |
