Pharmaceutical composition and method for the suppression of factor VIII inhibitor production.

摘要

A pharmaceutical composition suitable for administration to human beings for suppressing the production of factor VIII inhibitor includes: an immune complex of factor VIII antigen component and factor VIII inhibitor component, the components being present in a ratio such that the inhibitor blocks essentially all relevant binding sites of the antigen; and a pharmacologically acceptable carrier or diluent. The invention also provides a method of administering the compositions to suppress the production of inhibitor to factor VIII.