发明名称 |
Prostaglandin derivatives, their preparation and their therapeutic use. |
摘要 |
<p>Prostaglandin derivatives having an oxo group at specified positions in the alpha side chain and having the formula (I): <CHEM> (in which R<1> - R<5> represent hydrogen or various organic groups, m is 0 - 5 and n is 2 - 5) have a variety of physiological effects, notably a strong anti-ulcer activity accompanied by a limited ability to inhibit blood platelet aggregation. They may be prepared by the oxidation of a corresponding compound in which the oxo group in the cyclopentane ring, and optionally that in the alpha side chain, is replaced by a hydroxy group.</p> |
申请公布号 |
EP0276124(A2) |
申请公布日期 |
1988.07.27 |
申请号 |
EP19880300415 |
申请日期 |
1988.01.19 |
申请人 |
SANKYO COMPANY LIMITED |
发明人 |
KOJIMA, KOICHI;AMEMIYA, SHIGEO;KOYAMA, KAZUO;IWATA, NOBUYOSHI;TABATA, KEIICHI |
分类号 |
C07C405/00;(IPC1-7):C07C177/00 |
主分类号 |
C07C405/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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