| 发明名称 |
PROCESS FOR THE PREPARATION OF 1-(2-TETRAHYDROFURYL)- 5-FLUOROURACIL |
| 摘要 |
<p>PROCESS FOR THE PREPARATION OF 1-(2-TETRAHYDROFURYL)-5-FLUOROURACIL A process for efficiently preparing 1-(2-tetrahydrofuryl)-5-fluorouracil useful as an antitumor agent or an antiviral agent which comprises reacting 5-fluorouracil with 2,3-dihydrofuran. This reaction proceeds advantageously in the presence of a reacti accelerator such as a Lewis acid in a polar solvent such as pyridine.</p> |
| 申请公布号 |
CA1114376(A) |
申请公布日期 |
1981.12.15 |
| 申请号 |
CA19760267561 |
申请日期 |
1976.12.09 |
| 申请人 |
MITSUI TOATSU KAGAKU KABUSHIKI KAISHA (MITSUI TOATSU CHEM., INC.) |
发明人 |
KOJIMA, ATSUSHI;KOHNO, YOSHITSUGU;IKE, YOSHIMASA;YOKOYAMA, TATSURO;ODATE, MAKOTO |
| 分类号 |
A61K31/505;C07D;C07D239/00;C07D239/10;C07D239/30;C07D239/54;C07D307/04;C07D307/22;C07D405/04;(IPC1-7):07D405/04 |
主分类号 |
A61K31/505 |
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