| 发明名称 |
PYRAZOLOPHENYL-PYRIDINE COMPOUND, PHARMACEUTICAL COMPOSITION COMPRISING SAME, AND USE THEREOF |
| 摘要 |
The present invention relates to the field of pharmaceutical chemistry and pharmacotherapeutics, and in particular relates to a compound of general formula I as multi-targeted receptor tyrosine kinase inhibitors, such as EGFR, Her2, VEGFR and FGFR, and enantiomers, diastereoisomers, racemes and mixtures thereof, or pharmaceutical salt thereof, preparation method thereof, pharmaceutical composition comprising the compound, and the use thereof. |
| 申请公布号 |
WO2016188481(A1) |
申请公布日期 |
2016.12.01 |
| 申请号 |
WO2016CN83652 |
申请日期 |
2016.05.27 |
| 申请人 |
SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES |
发明人 |
LIU, Hong;GENG, Meiyu;ZHU, Wei;HUANG, Min;CHEN, Xianjie;LIU, Hongchun;HE, Yulong;LI, Chunpu;DING, Jian;JIANG, Hualiang;CHEN, Kaixian |
| 分类号 |
C07D401/04;A61K31/4439;A61K31/444;A61K31/4709;A61K31/501;A61K31/506;A61P35/00;A61P35/02;C07D401/14;C07D405/14;C07D409/14 |
主分类号 |
C07D401/04 |
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