| 发明名称 |
INCREASING STORAGE OF VITAMIN A, VITAMIN D AND/OR LIPIDS |
| 摘要 |
The present disclosure provides compositions that include a nanoparticle and a compound that reduces the biological activity of one or more bromodomain and extra-terminal family member (BET) proteins (e.g., a bromodomain inhibitor), and methods of using such compounds to increase retention or storage of vitamin A, vitamin D, and/or lipids by a cell, such as an epithelial or stellate cell. |
| 申请公布号 |
US2016331760(A1) |
申请公布日期 |
2016.11.17 |
| 申请号 |
US201615226052 |
申请日期 |
2016.08.02 |
| 申请人 |
Salk Institute for Biological Studies |
发明人 |
Evans Ronald M.;Downes Michael;Sherman Mara;Ding Ning |
| 分类号 |
A61K31/551;A61K45/06;A61K31/7068;A61K9/14 |
主分类号 |
A61K31/551 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A composition comprising:
a nanoparticle; and a compound that reduces the biological activity of one or more bromodomain and extra-terminal family member (BET) proteins. |
| 地址 |
La Jolla CA US |
