Ferroporphyrin Solid Dispersion and Preparation Method Therefor

摘要

Disclosed are a ferroporphyrin solid dispersion, preparation method therefor and a pharmaceutical composition comprising the solid dispersion, wherein the weight ratio of ferroporphyrin to the carrier material in the dispersion is 1:1-1:10. The solid dispersion of the present invention masks the undesirable taste of ferroporphyrin, ameliorates irritation thereof to the digestive tract, and at the same time increases the solubility thereof and improves the bioavailability thereof.

主权项

1. A porphyrin iron solid dispersion, comprising porphyrin iron and a carrier material, wherein said carrier material is selected from one or more of polymers comprising vinylpyrrolidone units, or mixtures thereof; polymers comprising ethylene glycol units; and celluloses or cellulose esters.