发明名称 |
METHOD FOR SUPPRESSING NONSPECIFIC SIGNALS FROM CONTAMINANTS IN AN IMMUNOASSAY USING SURFACE PLASMON-FIELD ENHANCED FLUORESCENCE SPECTROSCOPY (SPFS) |
摘要 |
An object of the present invention is to provide a method of suppressing, in an immunoassay using surface plasmon-field enhanced fluorescence spectroscopy (SPFS), nonspecific signals generated by nonspecific adsorption of contaminants contained in a sample to an SPFS sensor section (e.g., a primary antibody, a solid-phase layer and a metal thin film).;The present invention relates to a method of suppressing nonspecific signals originating from contaminants in an immunoassay using surface plasmon-field enhanced fluorescence spectroscopy (SPFS) (including cases where a receptor for a compound to be measured is used in place of a primary antibody), the method comprising performing at least one of the following pretreatments:
(1) a pretreatment of adding an acid or an alkali to a sample;(2) a pretreatment of adding a metal ion to the sample; and(3) a pretreatment of heating the sample. |
申请公布号 |
US2015309019(A1) |
申请公布日期 |
2015.10.29 |
申请号 |
US201314649770 |
申请日期 |
2013.11.08 |
申请人 |
Konica Minolta, Inc. |
发明人 |
KANEKO Tomonori;ISODA Takeshi |
分类号 |
G01N33/543;G01N21/64 |
主分类号 |
G01N33/543 |
代理机构 |
|
代理人 |
|
主权项 |
1. A method of suppressing nonspecific signals originating from contaminants in an immunoassay using surface plasmon-field enhanced fluorescence spectroscopy (SPFS) (including cases where a receptor for a compound to be measured is used in place of a primary antibody), said method comprising performing at least one of the following pretreatments:
(1) a pretreatment of adding an acid or an alkali to a sample; (2) a pretreatment of adding a metal ion to said sample; and (3) a pretreatment of heating said sample. |
地址 |
Chiyoda-ku, Tokyo JP |