发明名称 |
Methods for treating skin infection by administering an IL-4R antagonist |
摘要 |
The present invention provides methods for treating, preventing or ameliorating skin infections, including bacterial and viral infections. In certain embodiments, the invention provides methods to reduce skin infection in a patient with atopic dermatitis (AD). Also provided are methods for improving skin barrier function, and methods for reducing the risk of inflammation due to microbial infection in a patient in need thereof. The methods of the present invention comprise administering to a patient in need thereof a pharmaceutical composition comprising an interleukin-4 receptor (IL-4R) antagonist such as an anti-IL-4R antibody. |
申请公布号 |
US2015246973(A1) |
申请公布日期 |
2015.09.03 |
申请号 |
US201514632988 |
申请日期 |
2015.02.26 |
申请人 |
Regeneron Pharmaceuticals, Inc. ;Sanofi |
发明人 |
Graham Neil;Ardeleanu Marius;Radin Allen;Hamilton Jennifer D.;Teper Ariel |
分类号 |
C07K16/28;A61K39/395;A61K45/06 |
主分类号 |
C07K16/28 |
代理机构 |
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代理人 |
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主权项 |
1. A method for treating, preventing or ameliorating a skin infection comprising administering a pharmaceutical composition comprising a therapeutically effective amount of an interleukin-4 receptor (IL-4R) antagonist to a subject in need thereof. |
地址 |
Tarrytown NY US |