发明名称 Methods for treating skin infection by administering an IL-4R antagonist
摘要 The present invention provides methods for treating, preventing or ameliorating skin infections, including bacterial and viral infections. In certain embodiments, the invention provides methods to reduce skin infection in a patient with atopic dermatitis (AD). Also provided are methods for improving skin barrier function, and methods for reducing the risk of inflammation due to microbial infection in a patient in need thereof. The methods of the present invention comprise administering to a patient in need thereof a pharmaceutical composition comprising an interleukin-4 receptor (IL-4R) antagonist such as an anti-IL-4R antibody.
申请公布号 US2015246973(A1) 申请公布日期 2015.09.03
申请号 US201514632988 申请日期 2015.02.26
申请人 Regeneron Pharmaceuticals, Inc. ;Sanofi 发明人 Graham Neil;Ardeleanu Marius;Radin Allen;Hamilton Jennifer D.;Teper Ariel
分类号 C07K16/28;A61K39/395;A61K45/06 主分类号 C07K16/28
代理机构 代理人
主权项 1. A method for treating, preventing or ameliorating a skin infection comprising administering a pharmaceutical composition comprising a therapeutically effective amount of an interleukin-4 receptor (IL-4R) antagonist to a subject in need thereof.
地址 Tarrytown NY US