发明名称 Chemical compounds
摘要 Compounds of Formula I and methods for treating metabolic disorders are disclosed.;
申请公布号 US9040518(B2) 申请公布日期 2015.05.26
申请号 US201113640166 申请日期 2011.04.27
申请人 GlaxoSmithKline LLC 发明人 Aquino Christopher Joseph;Collins Jon Loren;Cowan David John;Wu Yulin
分类号 A61K31/554;C07D281/10;C07D417/06;C07F9/6541 主分类号 A61K31/554
代理机构 代理人 Brink Robert H.
主权项 1. A compound of Formula Iwherein R1 is H, Cl, Br, N(CH3)2, or methoxy; R2 is H or OH; each R3 is independently C1-6alkyl; X is CH2, C(O), or CH═CH; Q is C0-6alkyl; R4 is OH, SO3H, CO2H, PO3H2, CONR5R5, NR5R5; or NHC(O)CH2NR5R5; each R5 is independently H, OH, C1-6alkyl, C0-6alkylCO2H, C0-6 alkylSO3H, C0-6alkylPO3H2, C(O)C0-6alkylCO2H, C(O)C0-6alkylSO3H, C(O)C0-6alkylPO3H2, or CH(R7)C0-6alkyCO2H; and R7 is C0-6alkylCO2H, C0-6alkylOH, C0-6alkylSO3H, or C0-6alkylPO3H2.
地址 Wilmington, New Castle DE US