UV cured gel and method of making

摘要

A method of UV curing and corresponding resulting non-polymeric cross-linked gel are provided. The cross-linked gel can be combined with a medical device structure. The cross-linked gel can provide anti-adhesion characteristics, in addition to improved healing and anti-inflammatory response. The cross-linked gel is generally formed of a naturally occurring oil, or an oil composition formed in part of a naturally occurring oil, that is at least partially cured forming a cross-linked gel derived from at least one fatty acid compound. In addition, the oil composition can include a therapeutic agent component, such as a drug or other bioactive agent. The curing method can vary the application of UV light in both intensity and duration to achieve a desired amount of cross-linking forming the gel.

主权项

1. An ultraviolet (UV) light cured gel, the gel comprising:
fish oil, wherein the fish oil comprises unsaturated fatty acids; wherein the fish oil is in a state of having been cured by application of UV light to cross link the unsaturated fatty acids by ester bonds in a substantially random configuration to form the gel; wherein the gel is bioabsorbable; wherein the gel further comprises a therapeutic agent; and wherein the amount of curing is controlled by the application of the UV light in such a way that the gel is configured to provide controlled release of the therapeutic agent.