| 发明名称 |
CO-CRYSTALS OF TRAMADOL AND NSAIDs |
| 摘要 |
The present invention relates to co-crystals of tramadol and co-crystal formers selected from NSAIDs, processes for preparation of the same and their uses as medicaments or in pharmaceutical formulations, more particularly for the treatment of pain. |
| 申请公布号 |
US2014350110(A1) |
申请公布日期 |
2014.11.27 |
| 申请号 |
US201414324448 |
申请日期 |
2014.07.07 |
| 申请人 |
LABORATORIOS DEL DR. ESTEVE, S.A. |
发明人 |
BUSCHMANN Helmut Heinrich;SOLA CARANDELL Lluis;BENET BUCHHOLZ Jordi;CERON BERTRAN Jordi Carles;PLATA SALAMAN Carlos Ramon;TESSON Nicolas |
| 分类号 |
A61K31/192;A61K31/135 |
主分类号 |
A61K31/192 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A co-crystal comprising tramadol either as a free base or as a physiologically acceptable salt and at least one NSAID, wherein the NSAID is naproxen, its enantiomers or salts thereof. |
| 地址 |
Barcelona ES |
