| 发明名称 | Cellulase Cel5H related reagents and their use in microorganisms | ||
| 摘要 | The invention relates to applications of the cellulase Cel5H of Saccharophagus degradans and its homologues, functional fragments and/or variants and engineered forms thereof, in the context of recombinant, more particularly solventogenic microorganisms, more particularly C. acetobutylicum. The invention also characterizes a novel domain of the Cel5H cellulase with a putative cellulose-binding module function, and its uses in chimeric proteins for depolymerization of cellulose containing substrates. | ||
| 申请公布号 | US8871479(B2) | 申请公布日期 | 2014.10.28 |
| 申请号 | US200913131478 | 申请日期 | 2009.11.26 |
| 申请人 | Total Marketing Services;Le Centre National de Recherche Scientifiques (CNRS);L'Institut National des Sciences Appliquees (INSA);Universite d'Aix-Marseille | 发明人 | Fierobe Henri-Pierre;Chanal-Vial Angélique;Molinier Anne-Laure;Tardif Chantal;Dedieu Luc |
| 分类号 | C12P1/04;C12N1/20;C12P1/00;C08B37/00;C12N9/42;C07H21/04 | 主分类号 | C12P1/04 |
| 代理机构 | Hunton & Williams LLP | 代理人 | Hunton & Williams LLP |
| 主权项 | 1. A recombinant Clostridium bacterium transformed with and expressing the Cel5H polypeptide of Saccharophagus degradans strain 2-40 or a homologue thereof having at least 95% sequence identity with said Cel5H polypeptide of Saccharophagus degradans strain 2-40, wherein said recombinant bacterium is capable of secreting said Cel5H polypeptide and capable of degrading cellulose. | ||
| 地址 | Puteaux FR | ||