| 发明名称 |
Stem Cell Derived Factors for Treating Pathologic Conditions |
| 摘要 |
A purified paracrine factor of a mesenchymal stem cell, such as a Secreted frizzled related protein (Sfrp) is useful to reduce cell death an/or tissue injury associated with ischemic conditions. |
| 申请公布号 |
US2014296152(A1) |
申请公布日期 |
2014.10.02 |
| 申请号 |
US201414256174 |
申请日期 |
2014.04.18 |
| 申请人 |
THE BRIGHAM AND WOMEN'S HOSPITAL, INC. ;Duke University |
发明人 |
Dzau Victor J.;Mirotsou Maria |
| 分类号 |
A61K38/17 |
主分类号 |
A61K38/17 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A method of reducing cell death, comprising contacting an injured or diseased tissue with a composition comprising a purified paracrine factor of a mesenchymal stem cell (MSC), wherein said factor comprises SEQ ID NO:17 or a fragment thereof and wherein said tissue comprises neurological tissue. |
| 地址 |
Boston MA US |
