发明名称 |
Agents for preventing and treating disorders involving modulation of the ryanodine receptors |
摘要 |
The present invention provides compounds of Formula I and salts, hydrates, solvates, complexes, and prodrugs thereof. The present invention further provides methods for synthesizing compounds of Formula I. The invention additionally provides pharmaceutical compositions comprising the compounds of Formula I and methods of using the pharmaceutical compositions of Formula I to treat and prevent disorders and diseases associated with the RyR receptors that regulate calcium channel functioning in cells. |
申请公布号 |
US8710045(B2) |
申请公布日期 |
2014.04.29 |
申请号 |
US20100938098 |
申请日期 |
2010.11.02 |
申请人 |
MARKS ANDREW ROBERT;LANDRY DONALD W.;DENG SHIXIAN;THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK |
发明人 |
MARKS ANDREW ROBERT;LANDRY DONALD W.;DENG SHIXIAN |
分类号 |
A61P9/00;A61K31/553;A61K31/554;C07D281/02 |
主分类号 |
A61P9/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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