FLINDEROLE ANALOGUES AND PROCESS FOR SYNTHESIS THEREOF
摘要
The present invention discloses flinderole compounds/analogues of formula I and to a process for the preparation of same, comprising stereo- and regioselective [3+2] cycloaddition reaction of a tertiary alcohol (1a') and a sulphonated diene (1b') in presence of Lewis acid selected from Cu(OTf)2 or BF3OEt2 and a non-polar solvent at room temperature. The flinderole compounds /analogues of the instant invention and prepared by the process described therein is represented by the general formula I,(The formula I should be inserted here) wherein R1-R4 are described herein in the specification.
申请公布号
WO2012107934(A1)
申请公布日期
2012.08.16
申请号
WO2011IN00899
申请日期
2011.12.28
申请人
COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH;DETHE, DATTATRAYA, HANUMANT;ERANDE, ROHAN, DILIPRAO;RANJAN, ALOK