发明名称 |
IMPROVED ANTI-TNFR1 POLYPEPTIDES, ANTIBODY VARIABLE DOMAINS & ANTAGONISTS |
摘要 |
The invention relates to anti-TNFR1 polypeptides, antibody single variable domains (dAbs), antagonists and multispecific ligands, as well as methods and uses of these. The anti-TNFR1 polypeptides, antibody single variable domains (dAbs), antagonists and multispecific ligands are useful for treating and/or preventing inflammatory disease, such as arthritis or COPD, as well as for pulmonary administration, oral administration, delivery to the lung and delivery to the GI tract of a patient. |
申请公布号 |
WO2010094720(A2) |
申请公布日期 |
2010.08.26 |
申请号 |
WO2010EP52005 |
申请日期 |
2010.02.17 |
申请人 |
GLAXO GROUP LIMITED;DUFFIELD, STEPHEN;ENEVER, CAROLYN;LIU, HAIQUN;SCHON, OLIVER;SEPP, ARMIN;STOOP, ALLART ADRIAAN |
发明人 |
DUFFIELD, STEPHEN;ENEVER, CAROLYN;LIU, HAIQUN;SCHON, OLIVER;SEPP, ARMIN;STOOP, ALLART ADRIAAN |
分类号 |
C07K16/28;A61K39/395;A61K39/44;A61K47/48;A61P37/00 |
主分类号 |
C07K16/28 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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