The invention relates to therapeutic conjugates with improved ability to target various diseased cells containing a targeting moiety (such as an antibody or antibody fragment), a linker and a camptothecin as a therapeutic moiety, and further relates to processes for making and using the said conjugates.
申请公布号
WO2009100194(A2)
申请公布日期
2009.08.13
申请号
WO2009US33182
申请日期
2009.02.05
申请人
IMMUNOMEDICS, INC.;GOVINDAN, SERENGULAM V.;GOLDENBERG, DAVID M.;MOON, SUNG-JU
发明人
GOVINDAN, SERENGULAM V.;GOLDENBERG, DAVID M.;MOON, SUNG-JU