发明名称 OXIDATION PROCESS FOR PREPARING THE INTERMEDIATE 6.ALPHA., 9.ALPHA.- DIFLUORO-11.BETA., 17.ALPHA.-DIHYDROXY-16.ALPHA.-METHYL-ANDROST-1,4-DIEN-3- ONE 17.BETA.-CARBOXYLIC ACID
摘要 The present invention relates to a process for the preparation of a compound of formula (I) which comprises the following step: wherein step (a) comprises oxidation of a solution containing the compound of formula (II) wherein the solution is formed in a mixture of water and tetrahydrofuran.
申请公布号 HK1056179(A1) 申请公布日期 2009.07.17
申请号 HK20030106680 申请日期 2003.09.17
申请人 GLAXO GROUP LIMITED 发明人 ALBINSON, FREDERICK DAVID;COOTE, STEVEN JOHN;ROBINSON, JOHN MALCOLM
分类号 C07J;C07J3/00;C07J5/00;C07J17/00;C07J31/00 主分类号 C07J
代理机构 代理人
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