In one embodiment, there is disclosed a method of inducing an immune response in a subject comprising administering to the subject a Francisella bacterium that includes an alteration in the nucleic acid sequence encoding the mglA, iglA, iglB, iglC, or iglD gene of the bacterium.
申请公布号
WO2007101262(A3)
申请公布日期
2007.12.27
申请号
WO2007US63004
申请日期
2007.02.28
申请人
THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM;KLOSE, KARL, E.;ARULANANDAM, BERNARD, P.
