SYSTEM, CHAMBER, AND METHOD FOR FRACTIONATION, ELUTRIATION, AND DECONTAMINATION OF FLUIDS CONTAINING CELLULAR COMPONENTS

摘要

A chamber, duct system, and method for separating a selected component from and decontaminating a biological sample, such as a unit of blood product, to be stored for a storage interval between a donation and a subsequent transfusion. The method comprises exposing the biological sample to a first decontamination process prior to the storage interval wherein the first decontamination process is adapted to preserve the at least one component while eliminating and/or inactivating at least a portion of the plurality of contaminants (such as pathogens). The method further comprises exposing the biological sample to a second decontamination subsequent to the storage interval and prior to the transfusion of the biological sample. The second decontamination process is adapted to be capable of preserving the at least one component and inactivating and/or eliminating substantially all of the plurality of contaminants. Separating of the selected components utilizes a chamber comprising at least one duct that is capable of rotating about the central axis of a centrifuge device, wherein the geometrical design of the duct provides for a centrifugal force exerted on the selected component to be balanced relative to the drag force exerted on the selected component by the fluid as the selected component flows through the duct.