DIAGNOSTIC AGENTS AND USES THEREFOR

摘要

The present invention discloses methods and agents for diagnosing the presence or risk of developing type 1 diabetes in animals, especially vertebrate animals. Also disclosed are novel surrogate markers for this disease including members of the nuclear factor kB (NF-kB) pathway. The present invention also extends to methods for treating or preventing type 1 diabetes, which employ the diagnostic method of the invention.