| 摘要 |
PROBLEM TO BE SOLVED: To provide a simple method to keep a solution under a low pH for sterilization and to increase pH before injection without adding any composition. SOLUTION: A method to prepare a liquid product comprises: a process to prepare a product having pH at least similar to a desired final pH level; a process to decrease pH of the product lower than the desired final level; and a process to increase pH of the product toward the desired final pH level over a stated period by releasing carbon dioxide from the product. Preferably, the method includes a process to add a compound to generate carbon dioxide to the product. The method to prepare a medical solution is provided as one implement including a process to place the solution in a gas-permeable container and a process to let carbon dioxide permeate from the container until the desired pH is obtained. COPYRIGHT: (C)2007,JPO&INPIT
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