发明名称 |
METHODS OF TREATING CANCERS WITH SAHA, CARBOPLATIN, AND PACLITAXEL AND OTHER COMBINATION THERAPIES |
摘要 |
The present invention relates to a method of treating cancer in a subject in need thereof, by administering to a subject in need thereof an amount of a histone deacetylase (HDAC) inhibitor, e.g., suberoylanilide hydroxamic acid (SAHA), or a pharmaceutically acceptable salt or hydrate thereof, and an amount of one or more anticancer agents such as Carboplatin or Paclitaxel. The HDAC inhibitor and the anticancer agents may be administered to comprise therapeutically effective amounts. |
申请公布号 |
CA2626679(A1) |
申请公布日期 |
2007.05.18 |
申请号 |
CA20062626679 |
申请日期 |
2006.11.03 |
申请人 |
MERCK & CO., INC.;UNIVERSITY OF PITTSBURGH |
发明人 |
CHIAO, JUDY;PARADISE, CAROLYN;FRANKEL, STANLEY;RAMALINGAM, SURESH SAKKARAI;BELANI, CHANDRA |
分类号 |
A61K31/282;A61K31/16 |
主分类号 |
A61K31/282 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|