METHODS AND APPARATUSES FOR REDUCING EFFECTS OF MOLECULE ADSORPTION WITHIN MICROFLUIDIC CHANNELS

摘要

Microfluidic methods and apparatuses for reducing the effects of sample adsorption inside microfluidic channels are provided. According to one embodiment, a microfluidic chip comprising an analysis channel having a cross- sectional area at least two times larger than a cross-sectional area of a microscale channel in fluid communication with the analysis channel is provided that reduces the effects of compound adsorption on data analysis. According to another embodiment, methods for reducing the effect of molecule adsorption to a channel wall on analysis of a reaction in a microfluidic device and methods for making concentration dependent measurements in a microfluidic device are provided which utilize novel microfluidic chips disclosed herein.