发明名称 |
Derivatives of 2-(1-benzyl-1h-pyrazolo(3,4-b)pyridine-3-yl)- 5(-4-pyridiny)l-4- pyrimidinamines and the use thereof as quanylate cyclase stimulators |
摘要 |
The invention relates to novel chemical compounds of formula (I), which stimulate soluble guanylate cyclase, to the production and use thereof as medicament, particularly in the treatment of cardiovascular diseases and/or sexual dysfunction (I), wherein R<SUP>1</SUP>'' represents chlorine, cyano, trifluoromethyl or methoxy and R<SUP>2 </SUP>represents hydrogen or fluorine or R<SUP>1 </SUP>represents fluorine and R<SUP>2 </SUP>represents fluorine. The invention also relates to the salts, isomers and hydrates of said compounds.
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申请公布号 |
US2005222170(A1) |
申请公布日期 |
2005.10.06 |
申请号 |
US20050514909 |
申请日期 |
2005.05.16 |
申请人 |
WEIGAND STEFAN;BISCHOFF ERWIN;MUNTER KLAUS;STASCH JOHANNES-PETER;STAHL ELKE |
发明人 |
WEIGAND STEFAN;BISCHOFF ERWIN;MUNTER KLAUS;STASCH JOHANNES-PETER;STAHL ELKE |
分类号 |
A61K31/506;A61P7/02;A61P9/00;A61P9/10;A61P9/12;A61P15/10;A61P15/12;A61P43/00;C07D471/04;(IPC1-7):A61K31/506;C07D487/02 |
主分类号 |
A61K31/506 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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