| 发明名称 |
PROCESS FOR PREPARING 5-(4-FLUOROPHENYL)-1-[2-((2R,4R)-4-HYDROXY -6-OXO-TETRAHYDRO-PYRAN-2-YL)ETHYL]-2-ISOPROPYL-4-PHENYL-1H-PYRROLE-3-CARBOXYLIC ACID PHENYLAMIDE |
| 摘要 |
A method for preparing 5-(4-fluorophenyl)-I-[2-((2R, 4R)-4-hydroxy-6-oxo- tetrahydro-pyran-2-yl)-ethyl]-2-isopropyl-4-phenyl-1H-pyrrole-3-carboxylic acid phenylamide (I), a key intermediate in the synthesis of atorvastatin calcium, is described.
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| 申请公布号 |
CA2494269(A1) |
申请公布日期 |
2004.02.19 |
| 申请号 |
CA20032494269 |
申请日期 |
2003.07.25 |
| 申请人 |
WARNER-LAMBERT COMPANY LLC |
发明人 |
NELSON, JADE DOUGLAS;PAMMENT, MICHAEL GERARD |
| 分类号 |
A61K31/40;A61P3/06;C07B61/00;C07D207/34;C07D405/06;(IPC1-7):C07D405/06 |
主分类号 |
A61K31/40 |
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