发明名称 SUBSTITUTED 3-AMINO-THIENO[2,3-B]PYRIDINE-2-CARBOXYLIC ACID AMIDE COMPOUNDS AND PROCESSES FOR PREPARING AND THEIR USES
摘要 Disclosed are compounds of formula (I), wherein R1 and R2 are defined herein , which are useful as inhibitors of the kinase activity of the I.kappa.B kinas e (IKK) complex. The compounds are therefore useful in the treatment of IKK mediated diseases including autoimmune diseases inflammatory diseases and cancer. Also disclosed are pharmaceutical compositions comprising these compounds and processes for preparing these compounds.
申请公布号 CA2483890(A1) 申请公布日期 2003.12.18
申请号 CA20032483890 申请日期 2003.06.03
申请人 BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. 发明人 WU, JIANG-PING;CYWIN, CHARLES L.;CHEN, ZHIDONG;SORCEK, RONALD J.;NEMOTO, PETER ALLEN;SUN, SANXING;FLECK, ROMAN WOLFGANG;HAO, MING HONG;HICKEY, EUGENE RICHARD;MARSHALL, DANIEL R.;LIU, WEIMIN WILL;MORWICK, TINA M.;EMEIGH, JONATHAN
分类号 A61K31/38;A61K31/435;A61K31/4365;A61K31/438;A61K31/444;A61K31/4545;A61K31/496;A61K31/5377;A61K31/541;A61P1/04;A61P3/10;A61P9/00;A61P9/10;A61P11/00;A61P11/06;A61P11/08;A61P13/12;A61P17/00;A61P17/02;A61P17/06;A61P19/02;A61P21/04;A61P25/00;A61P25/04;A61P25/28;A61P29/00;A61P35/00;A61P35/02;A61P37/00;A61P37/06;A61P39/00;A61P43/00;C07B61/00;C07D495/04;C07D519/00;(IPC1-7):C07D495/04;C07D221/00;C07D333/00;A61K31/436 主分类号 A61K31/38
代理机构 代理人
主权项
地址