A pharmaceutical aerosol formulation comprising a particulate medicament, one or more fluorocarbon or hydrogen-containing fluorocarbon propellants and a compound of the general formula (I) or a salt or solvate thereof, wherein A represents a straight chain C1-16 alkylene substituted by n groups of formula B; n represents an integer 1 to 3; and B independently represents C1-4 fluoroalkylC0-6 alkylene-, C1-4 fluoroalkylC0-6 alkylene-O-, or C1-4 alkylC0-6 alkylene-O- wherein at least one substituent of formula B contains at least one fluorine atom and each C1-4 fluoroalkyl- moiety contains one or more fluorine atoms but not more than 3 consecutive perfluorinated carbon atoms. The invention also extends to uses of compounds of formula (I) and certain novel compounds within the definition of formula (I).
申请公布号
WO03013610(A3)
申请公布日期
2003.10.30
申请号
WO2002GB03586
申请日期
2002.08.02
申请人
GLAXO GROUP LIMITED;KALDOR, ISTVAN;LOOKER, BRIAN, EDGAR;LUNNISS, CHRISTOPHER, JAMES;REDGRAVE, ALISON, JUDITH