发明名称 |
METHOD FOR EXPANSION OF EPITHELIAL STEM CELLS |
摘要 |
Transplantation of epithelial stem cells, cultured ex vivo on specifically treated amniotic membrane, yields, with that amniotic membrane, a surgical graft having expanded epithelial stem cells. The method of creating this graft and the graft itself provide simple and effective means to reconstruct damaged tissue, a preferred example being corneal tissue. The source of the epithelial stem cells can be a very small explant from healthy autologous and allogeneic tissue biopsy. The amniotic membrane is treated such that its extracellular matrix is maintained, but its cells are killed. |
申请公布号 |
WO0180760(A8) |
申请公布日期 |
2003.05.30 |
申请号 |
WO2001US13321 |
申请日期 |
2001.04.25 |
申请人 |
TSAI, RAY, JUI-FANG;TSENG, SCHEFFER, C., G. |
发明人 |
TSAI, RAY, JUI-FANG |
分类号 |
A61L27/00;A61F2/14;A61K35/12;A61L27/36;A61L27/38;C12N5/00 |
主分类号 |
A61L27/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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