发明名称 THE TREATMENT OF SEXUAL DYSFUNCTION AND CARDIOVASCULAR DISEASE WITH QUINOLINONE ENANTIOMERS
摘要 Methods for treating specific patient groups for sexual dysfunction are provided. The methods of the present invention comprise the utilization of enantiomers of flosequinan, and pharmaceutical compositions comprising flosequinan enantiomers, in patients who are free of cardiac disease, who ha ve not been treated with a drug that causes hypotensive effects, and/or who hav e not been given organic nitrites or nitrates. Flosequinan enantiomers, and pharmaceutical compositions comprising flosequinan enantiomers are administered to patients intranasally, orally, topically, and/or through respiratory inhalation. Additionally, the present invention is directed to compositions and methods for treating cardiovascular disease. In a preferred embodiment, the present invention contemplates using the enantiomers of flosequinan (and formulations comprising flosequinan) in subjects not concurrently treated with nitrites or nitrates.
申请公布号 CA2435876(A1) 申请公布日期 2002.08.01
申请号 CA20022435876 申请日期 2002.01.24
申请人 R.T. ALAMO VENTURES I, LLC 发明人 CUTLER, NEAL R.;SRAMEK, JOHN
分类号 C07D215/36;A61K9/72;A61K31/47;A61P9/00;A61P15/00;A61P15/10;(IPC1-7):A61K31/47 主分类号 C07D215/36
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