| 摘要 |
The invention relates to 3-vinylpryrrole derivatives of general formula (I), wherein M represents a substituted peptide, a substituted hydantoin or thiohydantoin, tetrazole, lactam or lactone group, Y and Z independently represent a hydrogen atom, a halogen atom, a pseudohalogen, an optionally substituted alkyl, alkenyl, alkinyl, aralkyl, aralkenyl, aralkinyl, cycloalkyl, cycloalkenyl, cycloalkinyl, cycloaralkyl, cycloaralkenyl, cycloaralkinyl, aryl, alkoxy or aralkoxy group or a heterocyclic ring, and X is an optionally substituted and/or an optionally anellated or heteroanellated 3-pyrrole ring, and X and Y or X and Z or N and Z form part of a cycle. The invention further relates to pharmaceutical compounds that contain at least one of the above-mentioned compounds in combination with conventional excipients and/or adjuvants. |
