| 摘要 |
The present invention relates to methods and compositions for the diagnosis and treatment of hepatic, bone, or cardiovascular disorders. Specifically, the present invention identifies 2465 genes which are differentially expressed in hepatic, bone, or cardiovascular disorder states, relative to their expression in normal, or non-hepatic, non-bone, or non-cardiovascular disorder states, and/or in response to manipulations relevant to hepatic, bone, or cardiovascular disorders. The present invention describes methods for the diagnostic evaluation and prognosis of various hepatic, bone, or cardiovascular disorders, and for the identification of subjects exhibiting a predisposition to such conditions. The present invention also provides methods for the identification and therapeutic use of compounds as treatments of hepatic, bone, or cardiovascular disorders.
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