发明名称 |
Gepirone dosage form |
摘要 |
<p>Pharmaceutical compsn. for making oral extended release gepirone (I) dosage forms comprises: (a) 0.5-12 wt.% (I).HCl; (b) 70-85 wt.% cellulosic polymer matrix; (c) excipients. The release rate of (I) is such that 18-24 hrs. are required to attain 90-95% absorption of (I). Pref. (b) is hydroxypropylmethylcellulose with viscosity 1.5 x 104 - 1 x 106; and (c) is colourant, microcrystalline cellulose, colloidal silica and/or magnesium stearate.</p> |
申请公布号 |
GR3032598(T3) |
申请公布日期 |
2000.05.31 |
申请号 |
GR20000400296T |
申请日期 |
2000.02.09 |
申请人 |
BRISTOL-MYERS SQUIBB COMPANY |
发明人 |
DAVID, STEPHEN T.;GALLIAN, CLAUDE E.;CHOU, JOSEPH C.H. |
分类号 |
A61K9/22;A61K9/00;A61K9/20;A61K9/26;A61K9/50;A61K9/52;A61K31/505;A61K31/506;A61K47/02;A61K47/12;A61K47/38;A61P25/20;A61P25/22;A61P25/24;A61P25/26;(IPC1-7):A61K31/505;A61K9/16 |
主分类号 |
A61K9/22 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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