发明名称 Indolocarbazole derivatives and their use for the treatment of prostate gland disorders
摘要 <p>The invention relates to novel indolocarbazole derivatives, eg. of formula III &lt;CHEM&gt; (wherein: R&lt;1&gt; is selected from the group consisting of halogen, CH2OCONHR&lt;14&gt; and NHCO2R&lt;14&gt;; R&lt;2&gt; is selected from the group consisting of hydrogen and halogen; X is selected from the group consisting of CO2CH3, CH2OH and CONHR&lt;15&gt;; R&lt;14&gt; represents lower alkyl; and R&lt;15&gt; is hydrogen, hydroxy substituted lower alkyl, or aryl; with the proviso that when R&lt;1&gt; = halogen and R&lt;2&gt; = hydrogen, X is neither CO2CH3 nor CH2OH; and with the proviso that when R&lt;1&gt; = R&lt;2&gt; = halogen, X is not CO2CH3; and with the proviso that when R&lt;1&gt; = R&lt;2&gt; = Br, X is not CONHC6H5) which are useful in the treatment of pathological conditions of the prostate gland.</p>
申请公布号 EP0839814(A2) 申请公布日期 1998.05.06
申请号 EP19980200023 申请日期 1994.05.27
申请人 CEPHALON, INC.;KYOWA HAKKO KOGYO CO., LTD. 发明人 DIONNE, CRAIG A.;CONTRERAS, PATRICIA C.;MURAKATA, CHIKARA
分类号 A61K31/553;A61K31/407;A61K31/5395;A61K31/55;A61P13/08;A61P35/00;A61P43/00;C07D487/14;C07D498/22;C07H19/04;(IPC1-7):C07D498/22 主分类号 A61K31/553
代理机构 代理人
主权项
地址