NEW CEPHALOSPORIN COMPOUND AND ITS PRODUCTION

摘要

PURPOSE:To provide a new cephalosporin compound useful as an antibacterial antibiotic substance. CONSTITUTION:The compound of formula (R is H or lower alkyl) and its addition salt, e.g. CXL-1. The compound of formula can be produced e.g. by adding an oxidase, preferably laccase (at a concentration of 10-1007mug/mL) to 4- hydroxybenzyl cephalosporanic acid and reacting the components at 25-40 deg.C and pH 4-7 under stirring or shaking.