发明名称 |
Thermally reversible polyurethane hydrogels and cosmetic, biological and medical uses |
摘要 |
Thermally reversible polyurethane hydrogels are formed by adding water to a gel forming hydrophilic polyurethane polymer produced by reacting under anhydrous conditions a non-aromatic organic diisocyanate with a glycol component in an NCO/OH mole weight ratio of from about 0.900/1 to about 0.980/1, the glycol component having a number average molecular weight of from about 1000 to 3500 wherein the percentage by weight of the diisocyanate in the reaction mixture is from about 7% to about 20%. The hydrogels are solids at room temperature but liquify at higher temperatures such as body temperature and therefore are useful as carriers for the protection, delivery and sustained release of a variety of active agents including pharmaceuticals, cosmetics, living cells and organisms.
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申请公布号 |
US5000955(A) |
申请公布日期 |
1991.03.19 |
申请号 |
US19900559513 |
申请日期 |
1990.07.23 |
申请人 |
TYNDALE PLAINS-HUNTER LTD. |
发明人 |
GOULD, FRANCIS E.;JOHNSTON, CHRISTIAN W.;SEEMS, GEORGE E. |
分类号 |
A61K8/04;A61K8/87;A61K9/20;A61K47/34;A61Q15/00;A61Q17/00;A61Q19/00;C08G18/48;C08G18/66;C08G18/73;C08G18/75;C12N1/20 |
主分类号 |
A61K8/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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