Toxic effects of cocaine can be blocked by chronic administration of carbamazepine in amount sufficient to achieve a 4-12 mu g/ml blood concentration. In addition, the dosing with carbamazepine blocks the reinforcing effects of the cocaine, thus decreasing the likelihood of development of addiction to cocaine.
申请公布号
WO9010446(A1)
申请公布日期
1990.09.20
申请号
WO1990US01059
申请日期
1990.03.01
申请人
THE UNITED STATES OF AMERICA, REPRESENTED BY THE S
发明人
WEISS, SUSAN, R., B.;POST, ROBERT, M.;AIGNER, THOMAS, G.