摘要 |
1. Process for the manufacture of 15 alpha-hydroxy-4-androstene-3,17-dione by the microbiological hydroxylation of 4-androstene-13,17-dione characterised in that Penicillium stoloniferum CBS P 102, Penicillium melinii CBS P 30 or Fusarium oxysporum f. vasinfectum ATCC 7808 are used for the fermentation. |