发明名称 |
Process for the preparation of 2-[2'-(optionally substituted, amino)thiazol-4'-yl]-2-[oximino]acetic acids and N-(benzyloxycarbonyl)thioureas |
摘要 |
The invention relates to a process for the preparation of 2-[2'-(optionally substituted, amino)-thiazol-4'-yl]-2-[oximino]acetic acids of the general formula <IMAGE> in which R and R1 have the meanings given in Claim 1, in which optionally substituted, N-(benzyloxycarbonyl)thioureas of the general formula III are reacted with C1 to C4-alkyl esters of 2-oximino-3-oxo-4-halo- or 2-oximino-3-oxo-4,4-dihalobutyric acids of the general formula IV, after which the C1 to C4-alkyl esters of the 2-[2'-(optionally substituted, amino)thiazol-4'-yl]-2-[oximino]acetic acids of the general formula I obtained are converted into other and/or reactive acyl derivatives.
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申请公布号 |
DE3436674(A1) |
申请公布日期 |
1985.04.25 |
申请号 |
DE19843436674 |
申请日期 |
1984.10.05 |
申请人 |
BIOGAL GYOGYSZERGYAR |
发明人 |
TOLDY,LAJOS,DR.;REZESSY,BELA;FEHER,GABOR;TOTH,ISTVAN,DR. |
分类号 |
C07D277/20;C07D277/38;C07D277/40;C07D277/42;C07D277/46;C07D277/48;(IPC1-7):C07D277/46 |
主分类号 |
C07D277/20 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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