发明名称 Process for the preparation of polyvalent virus vaccines in a single cell system, such polyvalent vaccines and their application.
摘要 <p>A polyvalent virus vaccine comprising a rabies virus and a canine distemper virus, and substantially free from tissue material, is prepared by propagating the viruses in a single cell system.</p><p>Preferably the rabies strain no. 675, deposited with the Czechoslovak National Collection of Type Cultures of the Institute of Hygiene and Epidemiology in Prague under CNCTC no. A 04/77, is used for this purpose.</p><p>The preparation process is preferably carried out by first infecting a suitable single cell system with a rabies virus strain, propagating the rabies virus and then infecting the cell system with at least a canine distemper virus, propagating the viruses and preparing from the propagation product the polyvalent vaccine.</p><p>The so abtained polyvalent virus vaccine may be used for a method for immunisation of warm blooded animals comprising inocculation of the animal with such vaccine.</p>
申请公布号 EP0023731(A2) 申请公布日期 1981.02.11
申请号 EP19800200653 申请日期 1980.07.04
申请人 GIST-BROCADES N.V. 发明人 BIJLENGA, GOSSE
分类号 A61K39/175;A61K39/205;A61K39/295;(IPC1-7):61K39/295;12N7/00 主分类号 A61K39/175
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