摘要 |
<p>A polyvalent virus vaccine comprising a rabies virus and a canine distemper virus, and substantially free from tissue material, is prepared by propagating the viruses in a single cell system.</p><p>Preferably the rabies strain no. 675, deposited with the Czechoslovak National Collection of Type Cultures of the Institute of Hygiene and Epidemiology in Prague under CNCTC no. A 04/77, is used for this purpose.</p><p>The preparation process is preferably carried out by first infecting a suitable single cell system with a rabies virus strain, propagating the rabies virus and then infecting the cell system with at least a canine distemper virus, propagating the viruses and preparing from the propagation product the polyvalent vaccine.</p><p>The so abtained polyvalent virus vaccine may be used for a method for immunisation of warm blooded animals comprising inocculation of the animal with such vaccine.</p> |