发明名称 SIRTUIN INDUCER, TISSUE REPAIRING AGENT, HEPATOCYTE GROWTH FACTOR INDUCER, TISSUE HOMEOSTASIS MAINTENANCE AGENT, AND TLR4 AGONIST, HAVING HYALURONIC ACID FRAGMENT AS ACTIVE INGREDIENT
摘要 Provided are a sirtuin inducer, a tissue repairing agent, a hepatocyte growth factor inducer, a tissue homeostasis maintenance agent, and a TLR4 agonist, which utilize a hyaluronic acid fragment as an active ingredient. A hyaluronic acid fragment selected from sizes of 2 to 20 sugar units, a pharmaceutically acceptable salt thereof, or pharmaceutically acceptable solvates thereof, is employed as the active ingredient for the sirtuin inducer, tissue repairing agent, hepatocyte growth factor inducer, tissue homeostasis maintenance agent, or TLR4 agonist. The hyaluronic acid fragment is preferably selected from sizes of 3 to 10 sugar units, and more preferably selected from a size of 3 or 4 sugar units.
申请公布号 EP3100736(A1) 申请公布日期 2016.12.07
申请号 EP20160157640 申请日期 2013.02.21
申请人 Hyaluronan Research Institute, Inc. 发明人 ASARI, Akira
分类号 A61K31/728;A61K8/60;A61K8/73;A61K31/7016;A61K31/702;A61P3/04;A61P3/06;A61P3/10;A61P9/10;A61P9/12;A61P11/00;A61P13/12;A61P17/16;A61P19/02;A61P21/00;A61P25/00;A61P25/28 主分类号 A61K31/728
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